hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562

BACKGROUND: The hERG potassium channel can modulate the proliferation of the chronic myelogenous leukemic K562 cells, and its role in the erythroid differentiation of K562 cells still remains unclear. PRINCIPAL FINDINGS: The hERG potassium channel blockage by a new 36-residue scorpion toxin BmKKx2,...

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Detalles Bibliográficos
Autores principales: Ma, Jian, Hu, Youtian, Guo, Mingxiong, Huang, Zan, Li, Wenxin, Wu, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873423/
https://www.ncbi.nlm.nih.gov/pubmed/24386436
http://dx.doi.org/10.1371/journal.pone.0084903

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