9G4+ Antibodies Isolated from HIV-Infected Patients Neutralize HIV-1 and Have Distinct Autoreactivity Profiles

Potent HIV-1 specific broadly neutralizing antibodies (BNA) are uncommon in HIV infected individuals, and have proven hard to elicit by vaccination. Several, isolated monoclonal BNA are polyreactive and also recognize self-antigens, suggesting a breach of immune tolerance in persons living with HIV...

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Detalles Bibliográficos
Autores principales: Alcéna, Danielle C., Kobie, James J., Kaminski, Denise A., Rosenberg, Alexander F., Mattiacio, Jonelle L., Brewer, Matthew, Dewhurst, Stephen, Dykes, Carrie, Jin, Xia, Keefer, Michael C., Sanz, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873436/
https://www.ncbi.nlm.nih.gov/pubmed/24386452
http://dx.doi.org/10.1371/journal.pone.0085098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873436/
https://www.ncbi.nlm.nih.gov/pubmed/24386452
http://dx.doi.org/10.1371/journal.pone.0085098

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