Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen

T cell responses to enteric bacteria are important in inflammatory bowel disease. I2, encoded by the pfiT gene of Pseudomonas fluorescens, is a T-cell superantigen associated with human Crohn's disease. Here we report the crystal structure of pfiT at 1.7Å resolution and provide a functional ana...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Lihui, Chen, Hui, Brecher, Matthew B., Li, Zhong, Wei, Bo, Nandi, Bisweswar, Zhang, Jing, Ling, Hua, Winslow, Gary, Braun, Jonathan, Li, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873459/
https://www.ncbi.nlm.nih.gov/pubmed/24385909
http://dx.doi.org/10.1371/journal.ppat.1003837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873459/
https://www.ncbi.nlm.nih.gov/pubmed/24385909
http://dx.doi.org/10.1371/journal.ppat.1003837

Ejemplares similares