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The CD8-Derived Chemokine XCL1/Lymphotactin Is a Conformation-Dependent, Broad-Spectrum Inhibitor of HIV-1

CD8+ T cells play a key role in the in vivo control of HIV-1 replication via their cytolytic activity as well as their ability to secrete non-lytic soluble suppressive factors. Although the chemokines that naturally bind CCR5 (CCL3/MIP-1α, CCL4/MIP- 1β, CCL5/RANTES) are major components of the CD8-d...

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Detalles Bibliográficos
Autores principales:	Guzzo, Christina, Fox, Jamie, Lin, Yin, Miao, Huiyi, Cimbro, Raffaello, Volkman, Brian F., Fauci, Anthony S., Lusso, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873461/ https://www.ncbi.nlm.nih.gov/pubmed/24385911 http://dx.doi.org/10.1371/journal.ppat.1003852

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