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Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1

Malaria vaccine candidate Apical Membrane Antigen-1 (AMA1) induces protection, but only against parasite strains that are closely related to the vaccine. Overcoming the AMA1 diversity problem will require an understanding of the structural basis of cross-strain invasion inhibition. A vaccine contain...

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Detalles Bibliográficos
Autores principales:	Dutta, Sheetij, Dlugosz, Lisa S., Drew, Damien R., Ge, Xiopeng, Ababacar, Diouf, Rovira, Yazmin I., Moch, J. Kathleen, Shi, Meng, Long, Carole A., Foley, Michael, Beeson, James G., Anders, Robin F., Miura, Kazutoyo, Haynes, J. David, Batchelor, Adrian H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873463/ https://www.ncbi.nlm.nih.gov/pubmed/24385910 http://dx.doi.org/10.1371/journal.ppat.1003840

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