A common functional promoter variant links CNR1 gene expression to HDL cholesterol level

CB(1) receptor blockers increase HDL-C levels. Although genetic variation in the CB(1) receptor – encoded by the CNR1 gene – is known to influence HDL-C level as well, human studies conducted to date have been limited to genetic markers such as haplotype tagging SNPs. Here we identify rs806371 in th...

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Detalles Bibliográficos
Autores principales: Feng, Q, Vickers, KC, Anderson, MP, Levin, MG, Chen, W, Harrison, DG, Wilke, RA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873874/
https://www.ncbi.nlm.nih.gov/pubmed/23748922
http://dx.doi.org/10.1038/ncomms2973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873874/
https://www.ncbi.nlm.nih.gov/pubmed/23748922
http://dx.doi.org/10.1038/ncomms2973

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