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A common functional promoter variant links CNR1 gene expression to HDL cholesterol level
CB(1) receptor blockers increase HDL-C levels. Although genetic variation in the CB(1) receptor – encoded by the CNR1 gene – is known to influence HDL-C level as well, human studies conducted to date have been limited to genetic markers such as haplotype tagging SNPs. Here we identify rs806371 in th...
Autores principales: | Feng, Q, Vickers, KC, Anderson, MP, Levin, MG, Chen, W, Harrison, DG, Wilke, RA |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873874/ https://www.ncbi.nlm.nih.gov/pubmed/23748922 http://dx.doi.org/10.1038/ncomms2973 |
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