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NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies
Paraspeckles are subnuclear structures formed around nuclear paraspeckle assembly transcript 1 (NEAT1)/MENε/β long noncoding RNA (lncRNA). Here we show that paraspeckles become dramatically enlarged after proteasome inhibition. This enlargement is mainly caused by NEAT1 transcriptional up-regulation...
Autores principales: | Hirose, Tetsuro, Virnicchi, Giorgio, Tanigawa, Akie, Naganuma, Takao, Li, Ruohan, Kimura, Hiroshi, Yokoi, Takahide, Nakagawa, Shinichi, Bénard, Marianne, Fox, Archa H., Pierron, Gérard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873887/ https://www.ncbi.nlm.nih.gov/pubmed/24173718 http://dx.doi.org/10.1091/mbc.E13-09-0558 |
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