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Processive acceleration of actin barbed-end assembly by N-WASP
Neuronal Wiskott–Aldrich syndrome protein (N-WASP)–activated actin polymerization drives extension of invadopodia and podosomes into the basement layer. In addition to activating Arp2/3, N-WASP binds actin-filament barbed ends, and both N-WASP and barbed ends are tightly clustered in these invasive...
Autores principales: | Khanduja, Nimisha, Kuhn, Jeffrey R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873893/ https://www.ncbi.nlm.nih.gov/pubmed/24227886 http://dx.doi.org/10.1091/mbc.E12-11-0781 |
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