Cargando…
Taste Neurons Consist of Both a Large TrkB-Receptor-Dependent and a Small TrkB-Receptor-Independent Subpopulation
Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4) are two neurotrophins that play distinct roles in geniculate (taste) neuron survival, target innervation, and taste bud formation. These two neurotrophins both activate the tropomyosin-related kinase B (TrkB) receptor and the pan-neu...
Autores principales: | Fei, Da, Krimm, Robin F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873951/ https://www.ncbi.nlm.nih.gov/pubmed/24386206 http://dx.doi.org/10.1371/journal.pone.0083460 |
Ejemplares similares
-
TrkB expression and dependence divides gustatory neurons into three subpopulations
por: Rios-Pilier, Jennifer, et al.
Publicado: (2019) -
Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity
por: Vidaurre, Ó G, et al.
Publicado: (2012) -
Receptor-Independent Anti-Ferroptotic Activity of TrkB Modulators
por: Jakaria, Md., et al.
Publicado: (2022) -
Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists
por: Pankiewicz, Piotr, et al.
Publicado: (2021) -
Selective activation and down‐regulation of Trk receptors by neurotrophins in human neurons co‐expressing TrkB and TrkC
por: Ateaque, Sarah, et al.
Publicado: (2022)