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β1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis and Migration of Their Progeny
β1 integrin regulates multiple epithelial cell functions by connecting cells with the extracellular matrix (ECM). While β1 integrin-mediated signaling in murine epithelial stem cells is well-studied, its role in human adult epithelial progenitor cells (ePCs) in situ remains to be defined. Using micr...
Autores principales: | Ernst, Nancy, Yay, Arzu, Bíró, Tamás, Tiede, Stephan, Humphries, Martin, Paus, Ralf, Kloepper, Jennifer E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874009/ https://www.ncbi.nlm.nih.gov/pubmed/24386370 http://dx.doi.org/10.1371/journal.pone.0084356 |
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