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C3 Rho-Inhibitor for Targeted Pharmacological Manipulation of Osteoclast-Like Cells

The C3 toxins from Clostridium botulinum (C3bot) and Clostridium limosum (C3lim) as well as C3-derived fusion proteins are selectively taken up into the cytosol of monocytes/macrophages where the C3-catalyzed ADP-ribosylation of Rho results in inhibition of Rho-signalling and characteristic morpholo...

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Detalles Bibliográficos
Autores principales:	Tautzenberger, Andrea, Förtsch, Christina, Zwerger, Christian, Dmochewitz, Lydia, Kreja, Ludwika, Ignatius, Anita, Barth, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874027/ https://www.ncbi.nlm.nih.gov/pubmed/24386487 http://dx.doi.org/10.1371/journal.pone.0085695

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