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Transcription factor binding to Caenorhabditis elegans first introns reveals lack of redundancy with gene promoters

Gene expression is controlled through the binding of transcription factors (TFs) to regulatory genomic regions. First introns are longer than other introns in multiple eukaryotic species and are under selective constraint. Here we explore the importance of first introns in TF binding in the nematode...

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Detalles Bibliográficos
Autores principales: Fuxman Bass, Juan I., Tamburino, Alex M., Mori, Akihiro, Beittel, Nathan, Weirauch, Matthew T., Reece-Hoyes, John S., Walhout, Albertha J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874175/
https://www.ncbi.nlm.nih.gov/pubmed/24068555
http://dx.doi.org/10.1093/nar/gkt858

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