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PRMT5-mediated histone H4 arginine-3 symmetrical dimethylation marks chromatin at G + C-rich regions of the mouse genome
Symmetrical dimethylation on arginine-3 of histone H4 (H4R3me2s) has been reported to occur at several repressed genes, but its specific regulation and genomic distribution remained unclear. Here, we show that the type-II protein arginine methyltransferase PRMT5 controls H4R3me2s in mouse embryonic...
Autores principales: | Girardot, Michael, Hirasawa, Ryutaro, Kacem, Salim, Fritsch, Lauriane, Pontis, Julien, Kota, Satya K., Filipponi, Doria, Fabbrizio, Eric, Sardet, Claude, Lohmann, Felix, Kadam, Shilpa, Ait-Si-Ali, Slimane, Feil, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874197/ https://www.ncbi.nlm.nih.gov/pubmed/24097435 http://dx.doi.org/10.1093/nar/gkt884 |
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