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Scanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after γ-irradiation and bleomycin treatment

A common feature of DNA repair proteins is their mobilization in response to DNA damage. The ability to visualizing and quantifying the kinetics of proteins localizing/dissociating from DNA double strand breaks (DSBs) via immunofluorescence or live cell fluorescence microscopy have been powerful too...

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Detalles Bibliográficos
Autores principales: Abdisalaam, Salim, Davis, Anthony J., Chen, David J., Alexandrakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874206/
https://www.ncbi.nlm.nih.gov/pubmed/24137007
http://dx.doi.org/10.1093/nar/gkt908