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Controlling Mammalian Gene Expression by Allosteric Hepatitis Delta Virus Ribozymes

[Image: see text] We engineered small molecule responsive allosteric ribozymes based on the genomic hepatitis delta virus (HDV) ribozyme by replacing the P4-L4 stem-loop with an RNA aptamer through a connector stem. When embedded in the 3′ untranslated region of a reporter gene mRNA, these RNA devic...

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Detalles Bibliográficos
Autores principales:	Nomura, Yoko, Zhou, Linlin, Miu, Anh, Yokobayashi, Yohei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874218/ https://www.ncbi.nlm.nih.gov/pubmed/23697539 http://dx.doi.org/10.1021/sb400037a

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