Cargando…

Controlling Mammalian Gene Expression by Allosteric Hepatitis Delta Virus Ribozymes

[Image: see text] We engineered small molecule responsive allosteric ribozymes based on the genomic hepatitis delta virus (HDV) ribozyme by replacing the P4-L4 stem-loop with an RNA aptamer through a connector stem. When embedded in the 3′ untranslated region of a reporter gene mRNA, these RNA devic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nomura, Yoko, Zhou, Linlin, Miu, Anh, Yokobayashi, Yohei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874218/ https://www.ncbi.nlm.nih.gov/pubmed/23697539 http://dx.doi.org/10.1021/sb400037a

Ejemplares similares

High-throughput assay and engineering of self-cleaving ribozymes by sequencing
por: Kobori, Shungo, et al.
Publicado: (2015)

RNA ligase ribozymes with a small catalytic core
por: Nomura, Yoko, et al.
Publicado: (2023)

Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles
por: Nomura, Yoko, et al.
Publicado: (2019)

High‐Throughput Mutational Analysis of a Twister Ribozyme
por: Kobori, Shungo, et al.
Publicado: (2016)

Experimental exploration of a ribozyme neutral network using evolutionary algorithm and deep learning
por: Rotrattanadumrong, Rachapun, et al.
Publicado: (2022)

A novel structural rearrangement of hepatitis delta virus antigenomic ribozyme
por: Nehdi, Atef, et al.
Publicado: (2007)

Inspecting the Ribozyme Region of Hepatitis Delta Virus Genotype 1: Conservation and Variability
por: Pacin-Ruiz, Beatriz, et al.
Publicado: (2022)

Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirus
por: Wang, Chuan-Xi, et al.
Publicado: (2010)

Infectious Clones of Tomato Chlorosis Virus: Toward Increasing Efficiency by Introducing the Hepatitis Delta Virus Ribozyme
por: Navas-Hermosilla, Elisa, et al.
Publicado: (2021)

Hepatitis delta virus-like circular RNAs from diverse metazoans encode conserved hammerhead ribozymes
por: de la Peña, Marcos, et al.
Publicado: (2021)

Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries
por: Tseligka, Eirini D., et al.
Publicado: (2022)

Aptamer-based and aptazyme-based riboswitches in mammalian cells
por: Yokobayashi, Yohei
Publicado: (2019)

Engineered allosteric ribozymes that respond to specific divalent metal ions
por: Zivarts, Maris, et al.
Publicado: (2005)

An efficient platform for genetic selection and screening of gene switches in Escherichia coli
por: Muranaka, Norihito, et al.
Publicado: (2009)

Inverse Thio Effects in the Hepatitis Delta Virus Ribozyme Reveal that the Reaction Pathway Is Controlled by Metal Ion Charge Density
por: Thaplyal, Pallavi, et al.
Publicado: (2015)

Quantum Mechanical/Molecular Mechanical Free Energy Simulations of the Self-Cleavage Reaction in the Hepatitis Delta Virus Ribozyme
por: Ganguly, Abir, et al.
Publicado: (2014)

Controlling the rate of organic reactions: rational design of allosteric Diels-Alderase ribozymes
por: Amontov, Sergey, et al.
Publicado: (2006)

Small-Molecule Aptamer for Regulating RNA Functions in Mammalian Cells and Animals
por: Fukunaga, Keisuke, et al.
Publicado: (2023)

Self-powered RNA nanomachine driven by metastable structure
por: Kobori, Shungo, et al.
Publicado: (2019)

RNase footprinting demonstrates antigenomic hepatitis delta virus ribozyme structural rearrangement as a result of self-cleavage reaction
por: Savochkina, Larissa, et al.
Publicado: (2008)

Assessment of metal-assisted nucleophile activation in the hepatitis delta virus ribozyme from molecular simulation and 3D-RISM
por: Radak, Brian K., et al.
Publicado: (2015)

A RNase P Ribozyme Inhibits Gene Expression and Replication of Hepatitis B Virus in Cultured Cells
por: Yan, Bin, et al.
Publicado: (2023)

Silencing of Amyloid Precursor Protein Expression Using a New Engineered Delta Ribozyme
por: Ben Aissa, Manel, et al.
Publicado: (2012)

Selection of silk-binding peptides by phage display
por: Nomura, Yoko, et al.
Publicado: (2011)

Identification of an hepatitis delta virus-like ribozyme at the mRNA 5′-end of the L1Tc retrotransposon from Trypanosoma cruzi
por: Sánchez-Luque, Francisco J., et al.
Publicado: (2011)

The wide expansion of hepatitis delta virus-like ribozymes throughout trypanosomatid genomes is linked to the spreading of L1Tc/ingi clade mobile elements
por: Sánchez-Luque, Francisco José, et al.
Publicado: (2014)

Firefly Luciferase Mutant with Enhanced Activity and Thermostability
por: Pozzo, Tania, et al.
Publicado: (2018)

Antigenomic delta ribozyme variants with mutations in the catalytic core obtained by the in vitro selection method
por: Łęgiewicz, Michał, et al.
Publicado: (2006)

Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme
por: Prommana, Parichat, et al.
Publicado: (2013)

Dynamic signal processing by ribozyme-mediated RNA circuits to control gene expression
por: Shen, Shensi, et al.
Publicado: (2015)

Secondary structure confirmation and localization of Mg(2+) ions in the mammalian CPEB3 ribozyme
por: Skilandat, Miriam, et al.
Publicado: (2016)

Experimental Resurrection of Ancestral Mammalian CPEB3 Ribozymes Reveals Deep Functional Conservation
por: Bendixsen, Devin P., et al.
Publicado: (2021)

Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems
por: Jacobsen, Thomas, et al.
Publicado: (2020)

Infection by Hepatitis Delta Virus
por: Taylor, John M.
Publicado: (2020)

The unforeseeable hammerhead ribozyme
por: Hammann, Christian, et al.
Publicado: (2009)

Learning from ribozymes
por: Herschlag, Dan
Publicado: (2015)

A combinatorial method to isolate short ribozymes from complex ribozyme libraries
por: Arriola, Joshua T, et al.
Publicado: (2020)

A GTP-synthesizing ribozyme selected by metabolic coupling to an RNA polymerase ribozyme
por: Akoopie, Arvin, et al.
Publicado: (2021)

Hepatitis Delta Virus: A Peculiar Virus
por: Alves, Carolina, et al.
Publicado: (2013)

Hepatitis Delta Virus RNA Replication
por: Tseng, Chung-Hsin, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_gtrbt6a24mn4p3top1a185fpmb