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Muscle Changes in Aging: Understanding Sarcopenia

Muscle physiology in the aging athlete is complex. Sarcopenia, the age-related decrease in lean muscle mass, can alter activity level and affect quality of life. This review addresses the microscopic and macroscopic changes in muscle with age, recognizes contributing factors including nutrition and...

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Detalles Bibliográficos
Autores principales: Siparsky, Patrick N., Kirkendall, Donald T., Garrett, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874224/
https://www.ncbi.nlm.nih.gov/pubmed/24427440
http://dx.doi.org/10.1177/1941738113502296
Descripción
Sumario:Muscle physiology in the aging athlete is complex. Sarcopenia, the age-related decrease in lean muscle mass, can alter activity level and affect quality of life. This review addresses the microscopic and macroscopic changes in muscle with age, recognizes contributing factors including nutrition and changes in hormone levels, and identifies potential pharmacologic agents in clinical trial that may aid in the battle of this complex, costly, and disabling problem. Level of Evidence: Level 5.