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Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes
Succinate is a valuable platform chemical for multiple applications. Confronted with the exhaustion of fossil energy resources, fermentative succinate production from renewable biomass to replace the traditional petrochemical process is receiving an increasing amount of attention. During the past fe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874355/ https://www.ncbi.nlm.nih.gov/pubmed/24396827 http://dx.doi.org/10.1155/2013/723412 |
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author | Cao, Yujin Zhang, Rubing Sun, Chao Cheng, Tao Liu, Yuhua Xian, Mo |
author_facet | Cao, Yujin Zhang, Rubing Sun, Chao Cheng, Tao Liu, Yuhua Xian, Mo |
author_sort | Cao, Yujin |
collection | PubMed |
description | Succinate is a valuable platform chemical for multiple applications. Confronted with the exhaustion of fossil energy resources, fermentative succinate production from renewable biomass to replace the traditional petrochemical process is receiving an increasing amount of attention. During the past few years, the succinate-producing process using microbial fermentation has been made commercially available by the joint efforts of researchers in different fields. In this review, recent attempts and experiences devoted to reduce the production cost of biobased succinate are summarized, including strain improvement, fermentation engineering, and downstream processing. The key limitations and challenges faced in current microbial production systems are also proposed. |
format | Online Article Text |
id | pubmed-3874355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-38743552014-01-06 Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes Cao, Yujin Zhang, Rubing Sun, Chao Cheng, Tao Liu, Yuhua Xian, Mo Biomed Res Int Review Article Succinate is a valuable platform chemical for multiple applications. Confronted with the exhaustion of fossil energy resources, fermentative succinate production from renewable biomass to replace the traditional petrochemical process is receiving an increasing amount of attention. During the past few years, the succinate-producing process using microbial fermentation has been made commercially available by the joint efforts of researchers in different fields. In this review, recent attempts and experiences devoted to reduce the production cost of biobased succinate are summarized, including strain improvement, fermentation engineering, and downstream processing. The key limitations and challenges faced in current microbial production systems are also proposed. Hindawi Publishing Corporation 2013 2013-12-12 /pmc/articles/PMC3874355/ /pubmed/24396827 http://dx.doi.org/10.1155/2013/723412 Text en Copyright © 2013 Yujin Cao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Cao, Yujin Zhang, Rubing Sun, Chao Cheng, Tao Liu, Yuhua Xian, Mo Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes |
title | Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes |
title_full | Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes |
title_fullStr | Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes |
title_full_unstemmed | Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes |
title_short | Fermentative Succinate Production: An Emerging Technology to Replace the Traditional Petrochemical Processes |
title_sort | fermentative succinate production: an emerging technology to replace the traditional petrochemical processes |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874355/ https://www.ncbi.nlm.nih.gov/pubmed/24396827 http://dx.doi.org/10.1155/2013/723412 |
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