Cargando…

Cyclin D1 Induction of Dicer Governs MicroRNA Processing and Expression in Breast Cancer

Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates the pRB protein and promotes G(1)/S cell cycle progression and oncogenesis. Dicer is a central regulator of miRNA maturation, encoding an enzyme that cleaves double strand RNA or stem-loop-stem RNA into 20–25 nucleotide lon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Zuoren, Wang, Liping, Wang, Chenguang, Ju, Xiaoming, Wang, Min, Chen, Ke, Loro, Emanuele, Li, Zhiping, Zhang, Yuzhen, Wu, Kongming, Casimiro, Mathew C., Gormley, Michael, Ertel, Adam, Fortina, Paolo, Chen, Yihan, Tozeren, Aydin, Liu, Zhongmin, Pestell, Richard G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874416/ https://www.ncbi.nlm.nih.gov/pubmed/24287487 http://dx.doi.org/10.1038/ncomms3812

Ejemplares similares

Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis
por: Casimiro, Mathew C., et al.
Publicado: (2015)

Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome
por: Wang, Guangxue, et al.
Publicado: (2018)

A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation
por: Yu, Zuoren, et al.
Publicado: (2008)

Cyclin D1 integrates G9a-mediated histone methylation
por: Li, Zhiping, et al.
Publicado: (2019)

Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation
por: Chen, Ke, et al.
Publicado: (2020)

Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth
por: Pestell, Timothy G., et al.
Publicado: (2017)

Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
por: Gormley, Michael, et al.
Publicado: (2007)

Small Non-coding RNAs Govern Mammary Gland Tumorigenesis
por: Yu, Zuoren, et al.
Publicado: (2012)

Cyclin D1 Induces Chromosomal Instability
por: Casimiro, Mathew C., et al.
Publicado: (2012)

Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classification
por: Gormley, Michael, et al.
Publicado: (2008)

Kinase independent oncogenic cyclin D1
por: Casimiro, Mathew C., et al.
Publicado: (2015)

FXYD5 is a Marker for Poor Prognosis and a Potential Driver for Metastasis in Ovarian Carcinomas
por: Raman, Pichai, et al.
Publicado: (2015)

Switch-like genes populate cell communication pathways and are enriched for extracellular proteins
por: Ertel, Adam, et al.
Publicado: (2008)

Human and mouse switch-like genes share common transcriptional regulatory mechanisms for bimodality
por: Ertel, Adam, et al.
Publicado: (2008)

Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer
por: Chen, Ke, et al.
Publicado: (2013)

The membrane-associated form of cyclin D1 enhances cellular invasion
por: Chen, Ke, et al.
Publicado: (2020)

DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1
por: Sun, Xin, et al.
Publicado: (2015)

miRNAs regulate stem cell self-renewal and differentiation
por: Yu, Zuoren, et al.
Publicado: (2012)

CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma
por: Qi, Yongqiang, et al.
Publicado: (2019)

Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer
por: Di Sante, Gabriele, et al.
Publicado: (2017)

Pathway-specific differences between tumor cell lines and normal and tumor tissue cells
por: Ertel, Adam, et al.
Publicado: (2006)

Long and noncoding RNAs (lnc-RNAs) determine androgen receptor dependent gene expression in prostate cancer growth in vivo
por: Pestell, Richard G, et al.
Publicado: (2014)

The inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism
por: Xu, Shaohua, et al.
Publicado: (2015)

Ancestral protein reconstruction reveals evolutionary events governing variation in Dicer helicase function
por: Aderounmu, Adedeji M, et al.
Publicado: (2023)

Structure of precursor microRNA’s terminal loop regulates human Dicer’s dicing activity by switching DExH/D domain
por: Liu, Zhongmin, et al.
Publicado: (2014)

Endogenous Dach1 in cancer
por: Wu, Kongming, et al.
Publicado: (2015)

Small RNA zippers lock miRNA molecules and block miRNA function in mammalian cells
por: Meng, Lingyu, et al.
Publicado: (2017)

DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma
por: Mansouri, Sheila, et al.
Publicado: (2016)

DICER1 Syndrome: DICER1 Mutations in Rare Cancers
por: Robertson, Jake C., et al.
Publicado: (2018)

Dicing the Disease with Dicer: The Implications of Dicer Ribonuclease in Human Pathologies
por: Theotoki, Eleni I., et al.
Publicado: (2020)

Automated detection of regions of interest for tissue microarray experiments: an image texture analysis
por: Karaçali, Bilge, et al.
Publicado: (2007)

Domain Altering SNPs in the Human Proteome and Their Impact on Signaling Pathways
por: Liu, Yichuan, et al.
Publicado: (2010)

Modular composition predicts kinase/substrate interactions
por: Liu, Yichuan, et al.
Publicado: (2010)

Cyclin-dependent kinases govern formation and maintenance of the nucleolus
por: Sirri, Valentina, et al.
Publicado: (2002)

Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage
por: Marampon, Francesco, et al.
Publicado: (2015)

Acetylation-defective mutants of Pparγ are associated with decreased lipid synthesis in breast cancer cells
por: Tian, Lifeng, et al.
Publicado: (2014)

Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types
por: Dawany, Noor B, et al.
Publicado: (2010)

Phylogenetic Analysis of the Endoribonuclease Dicer Family
por: Gao, Zeqian, et al.
Publicado: (2014)

Correction: Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage
por: Marampon, Francesco, et al.
Publicado: (2016)

The paradox of dicer in cancer
por: Swahari, Vijay, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_n858u55dsjk7hb14uic9sb87u8