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Where is it and How Does it Get There – Intracellular Localization and Traffic of P-glycoprotein

P-glycoprotein (P-gp), an ATP-binding cassette, is able to transport structurally and chemically unrelated substrates. Over-expression of P-gp in cancer cells significantly decreases the intercellular amount of anticancer drugs, and results in multidrug resistance in cancer cells, a major obstacle i...

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Detalles Bibliográficos
Autor principal:	Fu, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874554/ https://www.ncbi.nlm.nih.gov/pubmed/24416721 http://dx.doi.org/10.3389/fonc.2013.00321

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