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Putting an ‘End’ to HIV mRNAs: capping and polyadenylation as potential therapeutic targets
Like most cellular mRNAs, the 5′ end of HIV mRNAs is capped and the 3′ end matured by the process of polyadenylation. There are, however, several rather unique and interesting aspects of these post-transcriptional processes on HIV transcripts. Capping of the highly structured 5′ end of HIV mRNAs is...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874655/ https://www.ncbi.nlm.nih.gov/pubmed/24330569 http://dx.doi.org/10.1186/1742-6405-10-31 |