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Putting an ‘End’ to HIV mRNAs: capping and polyadenylation as potential therapeutic targets

Like most cellular mRNAs, the 5′ end of HIV mRNAs is capped and the 3′ end matured by the process of polyadenylation. There are, however, several rather unique and interesting aspects of these post-transcriptional processes on HIV transcripts. Capping of the highly structured 5′ end of HIV mRNAs is...

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Detalles Bibliográficos
Autor principal: Wilusz, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874655/
https://www.ncbi.nlm.nih.gov/pubmed/24330569
http://dx.doi.org/10.1186/1742-6405-10-31

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