Primary Adrenal Lymphoma with Secondary Central Nervous System Involvement: A Case Report and Review of the Literature

Approximately 10%-20% of all systemic lymphomas have central nervous system (CNS) involvement, which has been correlated to a worsened prognosis. It is well known that secondary involvement of the adrenal glands may occur in up to 25% of patients during the course of diffuse lymphoma. Primary adrena...

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Detalles Bibliográficos
Autores principales: Aydın, Kübra, Okutur, Kerem, Bozkurt, Mustafa, Aydın, Özlem, Namal, Esat, Öztürk, Akın, Pilancı, Kezban Nur, Diz Küçükkaya, Reyhan, Demir, Osman Gökhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874975/
https://www.ncbi.nlm.nih.gov/pubmed/24385832
http://dx.doi.org/10.4274/Tjh.2012.0172
Descripción
Sumario:Approximately 10%-20% of all systemic lymphomas have central nervous system (CNS) involvement, which has been correlated to a worsened prognosis. It is well known that secondary involvement of the adrenal glands may occur in up to 25% of patients during the course of diffuse lymphoma. Primary adrenal lymphoma (PAL), however, is a different entity, and it is defined as the presence of adrenal lymphoma without evidence of either nodal involvement or leukemia. It has been shown that this occurrence is rarely accompanied by extranodal involvement, such as in the CNS. PAL exhibits a tendency for CNS relapse and this possibility should be examined even before symptoms are present. Herein we present a patient with PAL and secondary CNS involvement.

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