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Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients

Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML....

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Detalles Bibliográficos
Autores principales: Şahin, Fahri, Saydam, Güray, Cömert, Melda, Uz, Burak, Yavuz, Akif Selim, Turan, Esra, Yönal, İpek, Atay, Hilmi, Keltikli, Engin, Turgut, Mehmet, Pehlivan, Mustafa, Akay, Meltem Olga, Gürkan, Emel, Paydaş, Semra, Kahraman, Selda, Demirkan, Fatih, Kırkızlar, Onur, Akpınar, Seval, Pamuk, Gülsüm Emel, Demir, Muzaffer, Özbaş, Hasan Mücahit, Sönmez, Mehmet, Gültürk, Mine, Salihoğlu, Ayşe, Eşkazan, Ahmet Emre, Ar, Cem, Haydaroğlu Şahin, Handan, Öngören, Şeniz, Başlar, Zafer, Aydın, Yıldız, Yenere, Mustafa Nuri, Tüzüner, Nükhet, Ferhanoğlu, Burhan, Haznedaroglu, İbrahim C., İlhan, Osman, Soysal, Teoman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874976/
https://www.ncbi.nlm.nih.gov/pubmed/24385824
http://dx.doi.org/10.4274/tjh.2013.0151
Descripción
Sumario:Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML. But, it is stil needed to have registry results retrospectively to evaluate daily CML practices. Materials and Methods: In this article, we have evaluated 1133 patients’ results with CML in terms of demographical features, disease status, response, resistance and use of second-generation TKIs. Results: The response rate has been found relatively high in comparison with previously published articles, and we detected that there was a lack of appropriate and adequate molecular response assessment. Conclusion: We concluded that we need to improve registry systems and increase the availability of molecular response assessment to provide high-quality patient care. Conflict of interest:None declared.