Cargando…
Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML....
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874976/ https://www.ncbi.nlm.nih.gov/pubmed/24385824 http://dx.doi.org/10.4274/tjh.2013.0151 |
_version_ | 1782297300521975808 |
---|---|
author | Şahin, Fahri Saydam, Güray Cömert, Melda Uz, Burak Yavuz, Akif Selim Turan, Esra Yönal, İpek Atay, Hilmi Keltikli, Engin Turgut, Mehmet Pehlivan, Mustafa Akay, Meltem Olga Gürkan, Emel Paydaş, Semra Kahraman, Selda Demirkan, Fatih Kırkızlar, Onur Akpınar, Seval Pamuk, Gülsüm Emel Demir, Muzaffer Özbaş, Hasan Mücahit Sönmez, Mehmet Gültürk, Mine Salihoğlu, Ayşe Eşkazan, Ahmet Emre Ar, Cem Haydaroğlu Şahin, Handan Öngören, Şeniz Başlar, Zafer Aydın, Yıldız Yenere, Mustafa Nuri Tüzüner, Nükhet Ferhanoğlu, Burhan Haznedaroglu, İbrahim C. İlhan, Osman Soysal, Teoman |
author_facet | Şahin, Fahri Saydam, Güray Cömert, Melda Uz, Burak Yavuz, Akif Selim Turan, Esra Yönal, İpek Atay, Hilmi Keltikli, Engin Turgut, Mehmet Pehlivan, Mustafa Akay, Meltem Olga Gürkan, Emel Paydaş, Semra Kahraman, Selda Demirkan, Fatih Kırkızlar, Onur Akpınar, Seval Pamuk, Gülsüm Emel Demir, Muzaffer Özbaş, Hasan Mücahit Sönmez, Mehmet Gültürk, Mine Salihoğlu, Ayşe Eşkazan, Ahmet Emre Ar, Cem Haydaroğlu Şahin, Handan Öngören, Şeniz Başlar, Zafer Aydın, Yıldız Yenere, Mustafa Nuri Tüzüner, Nükhet Ferhanoğlu, Burhan Haznedaroglu, İbrahim C. İlhan, Osman Soysal, Teoman |
author_sort | Şahin, Fahri |
collection | PubMed |
description | Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML. But, it is stil needed to have registry results retrospectively to evaluate daily CML practices. Materials and Methods: In this article, we have evaluated 1133 patients’ results with CML in terms of demographical features, disease status, response, resistance and use of second-generation TKIs. Results: The response rate has been found relatively high in comparison with previously published articles, and we detected that there was a lack of appropriate and adequate molecular response assessment. Conclusion: We concluded that we need to improve registry systems and increase the availability of molecular response assessment to provide high-quality patient care. Conflict of interest:None declared. |
format | Online Article Text |
id | pubmed-3874976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-38749762014-01-02 Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients Şahin, Fahri Saydam, Güray Cömert, Melda Uz, Burak Yavuz, Akif Selim Turan, Esra Yönal, İpek Atay, Hilmi Keltikli, Engin Turgut, Mehmet Pehlivan, Mustafa Akay, Meltem Olga Gürkan, Emel Paydaş, Semra Kahraman, Selda Demirkan, Fatih Kırkızlar, Onur Akpınar, Seval Pamuk, Gülsüm Emel Demir, Muzaffer Özbaş, Hasan Mücahit Sönmez, Mehmet Gültürk, Mine Salihoğlu, Ayşe Eşkazan, Ahmet Emre Ar, Cem Haydaroğlu Şahin, Handan Öngören, Şeniz Başlar, Zafer Aydın, Yıldız Yenere, Mustafa Nuri Tüzüner, Nükhet Ferhanoğlu, Burhan Haznedaroglu, İbrahim C. İlhan, Osman Soysal, Teoman Turk J Haematol Research Article Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML. But, it is stil needed to have registry results retrospectively to evaluate daily CML practices. Materials and Methods: In this article, we have evaluated 1133 patients’ results with CML in terms of demographical features, disease status, response, resistance and use of second-generation TKIs. Results: The response rate has been found relatively high in comparison with previously published articles, and we detected that there was a lack of appropriate and adequate molecular response assessment. Conclusion: We concluded that we need to improve registry systems and increase the availability of molecular response assessment to provide high-quality patient care. Conflict of interest:None declared. Galenos Publishing 2013-12 2013-12-05 /pmc/articles/PMC3874976/ /pubmed/24385824 http://dx.doi.org/10.4274/tjh.2013.0151 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Şahin, Fahri Saydam, Güray Cömert, Melda Uz, Burak Yavuz, Akif Selim Turan, Esra Yönal, İpek Atay, Hilmi Keltikli, Engin Turgut, Mehmet Pehlivan, Mustafa Akay, Meltem Olga Gürkan, Emel Paydaş, Semra Kahraman, Selda Demirkan, Fatih Kırkızlar, Onur Akpınar, Seval Pamuk, Gülsüm Emel Demir, Muzaffer Özbaş, Hasan Mücahit Sönmez, Mehmet Gültürk, Mine Salihoğlu, Ayşe Eşkazan, Ahmet Emre Ar, Cem Haydaroğlu Şahin, Handan Öngören, Şeniz Başlar, Zafer Aydın, Yıldız Yenere, Mustafa Nuri Tüzüner, Nükhet Ferhanoğlu, Burhan Haznedaroglu, İbrahim C. İlhan, Osman Soysal, Teoman Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients |
title | Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients |
title_full | Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients |
title_fullStr | Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients |
title_full_unstemmed | Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients |
title_short | Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients |
title_sort | turkish chronic myeloid leukemia study: retrospective sectional analysis of cml patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874976/ https://www.ncbi.nlm.nih.gov/pubmed/24385824 http://dx.doi.org/10.4274/tjh.2013.0151 |
work_keys_str_mv | AT sahinfahri turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT saydamguray turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT comertmelda turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT uzburak turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT yavuzakifselim turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT turanesra turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT yonalipek turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT atayhilmi turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT keltikliengin turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT turgutmehmet turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT pehlivanmustafa turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT akaymeltemolga turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT gurkanemel turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT paydassemra turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT kahramanselda turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT demirkanfatih turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT kırkızlaronur turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT akpınarseval turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT pamukgulsumemel turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT demirmuzaffer turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT ozbashasanmucahit turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT sonmezmehmet turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT gulturkmine turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT salihogluayse turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT eskazanahmetemre turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT arcem turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT haydaroglusahinhandan turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT ongorenseniz turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT baslarzafer turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT aydınyıldız turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT yeneremustafanuri turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT tuzunernukhet turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT ferhanogluburhan turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT haznedarogluibrahimc turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT ilhanosman turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients AT soysalteoman turkishchronicmyeloidleukemiastudyretrospectivesectionalanalysisofcmlpatients |