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Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients

Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML....

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Autores principales: Şahin, Fahri, Saydam, Güray, Cömert, Melda, Uz, Burak, Yavuz, Akif Selim, Turan, Esra, Yönal, İpek, Atay, Hilmi, Keltikli, Engin, Turgut, Mehmet, Pehlivan, Mustafa, Akay, Meltem Olga, Gürkan, Emel, Paydaş, Semra, Kahraman, Selda, Demirkan, Fatih, Kırkızlar, Onur, Akpınar, Seval, Pamuk, Gülsüm Emel, Demir, Muzaffer, Özbaş, Hasan Mücahit, Sönmez, Mehmet, Gültürk, Mine, Salihoğlu, Ayşe, Eşkazan, Ahmet Emre, Ar, Cem, Haydaroğlu Şahin, Handan, Öngören, Şeniz, Başlar, Zafer, Aydın, Yıldız, Yenere, Mustafa Nuri, Tüzüner, Nükhet, Ferhanoğlu, Burhan, Haznedaroglu, İbrahim C., İlhan, Osman, Soysal, Teoman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874976/
https://www.ncbi.nlm.nih.gov/pubmed/24385824
http://dx.doi.org/10.4274/tjh.2013.0151
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author Şahin, Fahri
Saydam, Güray
Cömert, Melda
Uz, Burak
Yavuz, Akif Selim
Turan, Esra
Yönal, İpek
Atay, Hilmi
Keltikli, Engin
Turgut, Mehmet
Pehlivan, Mustafa
Akay, Meltem Olga
Gürkan, Emel
Paydaş, Semra
Kahraman, Selda
Demirkan, Fatih
Kırkızlar, Onur
Akpınar, Seval
Pamuk, Gülsüm Emel
Demir, Muzaffer
Özbaş, Hasan Mücahit
Sönmez, Mehmet
Gültürk, Mine
Salihoğlu, Ayşe
Eşkazan, Ahmet Emre
Ar, Cem
Haydaroğlu Şahin, Handan
Öngören, Şeniz
Başlar, Zafer
Aydın, Yıldız
Yenere, Mustafa Nuri
Tüzüner, Nükhet
Ferhanoğlu, Burhan
Haznedaroglu, İbrahim C.
İlhan, Osman
Soysal, Teoman
author_facet Şahin, Fahri
Saydam, Güray
Cömert, Melda
Uz, Burak
Yavuz, Akif Selim
Turan, Esra
Yönal, İpek
Atay, Hilmi
Keltikli, Engin
Turgut, Mehmet
Pehlivan, Mustafa
Akay, Meltem Olga
Gürkan, Emel
Paydaş, Semra
Kahraman, Selda
Demirkan, Fatih
Kırkızlar, Onur
Akpınar, Seval
Pamuk, Gülsüm Emel
Demir, Muzaffer
Özbaş, Hasan Mücahit
Sönmez, Mehmet
Gültürk, Mine
Salihoğlu, Ayşe
Eşkazan, Ahmet Emre
Ar, Cem
Haydaroğlu Şahin, Handan
Öngören, Şeniz
Başlar, Zafer
Aydın, Yıldız
Yenere, Mustafa Nuri
Tüzüner, Nükhet
Ferhanoğlu, Burhan
Haznedaroglu, İbrahim C.
İlhan, Osman
Soysal, Teoman
author_sort Şahin, Fahri
collection PubMed
description Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML. But, it is stil needed to have registry results retrospectively to evaluate daily CML practices. Materials and Methods: In this article, we have evaluated 1133 patients’ results with CML in terms of demographical features, disease status, response, resistance and use of second-generation TKIs. Results: The response rate has been found relatively high in comparison with previously published articles, and we detected that there was a lack of appropriate and adequate molecular response assessment. Conclusion: We concluded that we need to improve registry systems and increase the availability of molecular response assessment to provide high-quality patient care. Conflict of interest:None declared.
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spelling pubmed-38749762014-01-02 Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients Şahin, Fahri Saydam, Güray Cömert, Melda Uz, Burak Yavuz, Akif Selim Turan, Esra Yönal, İpek Atay, Hilmi Keltikli, Engin Turgut, Mehmet Pehlivan, Mustafa Akay, Meltem Olga Gürkan, Emel Paydaş, Semra Kahraman, Selda Demirkan, Fatih Kırkızlar, Onur Akpınar, Seval Pamuk, Gülsüm Emel Demir, Muzaffer Özbaş, Hasan Mücahit Sönmez, Mehmet Gültürk, Mine Salihoğlu, Ayşe Eşkazan, Ahmet Emre Ar, Cem Haydaroğlu Şahin, Handan Öngören, Şeniz Başlar, Zafer Aydın, Yıldız Yenere, Mustafa Nuri Tüzüner, Nükhet Ferhanoğlu, Burhan Haznedaroglu, İbrahim C. İlhan, Osman Soysal, Teoman Turk J Haematol Research Article Objective: here have been tremendous changes in treatment and follow-up of patients with chronic myeloid leukemia (CML) in the last decade. Especially, regular publication and updating of NCCN and ELN guidelines have provided enermous rationale and base for close monitorization of patients with CML. But, it is stil needed to have registry results retrospectively to evaluate daily CML practices. Materials and Methods: In this article, we have evaluated 1133 patients’ results with CML in terms of demographical features, disease status, response, resistance and use of second-generation TKIs. Results: The response rate has been found relatively high in comparison with previously published articles, and we detected that there was a lack of appropriate and adequate molecular response assessment. Conclusion: We concluded that we need to improve registry systems and increase the availability of molecular response assessment to provide high-quality patient care. Conflict of interest:None declared. Galenos Publishing 2013-12 2013-12-05 /pmc/articles/PMC3874976/ /pubmed/24385824 http://dx.doi.org/10.4274/tjh.2013.0151 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Şahin, Fahri
Saydam, Güray
Cömert, Melda
Uz, Burak
Yavuz, Akif Selim
Turan, Esra
Yönal, İpek
Atay, Hilmi
Keltikli, Engin
Turgut, Mehmet
Pehlivan, Mustafa
Akay, Meltem Olga
Gürkan, Emel
Paydaş, Semra
Kahraman, Selda
Demirkan, Fatih
Kırkızlar, Onur
Akpınar, Seval
Pamuk, Gülsüm Emel
Demir, Muzaffer
Özbaş, Hasan Mücahit
Sönmez, Mehmet
Gültürk, Mine
Salihoğlu, Ayşe
Eşkazan, Ahmet Emre
Ar, Cem
Haydaroğlu Şahin, Handan
Öngören, Şeniz
Başlar, Zafer
Aydın, Yıldız
Yenere, Mustafa Nuri
Tüzüner, Nükhet
Ferhanoğlu, Burhan
Haznedaroglu, İbrahim C.
İlhan, Osman
Soysal, Teoman
Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
title Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
title_full Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
title_fullStr Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
title_full_unstemmed Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
title_short Turkish Chronic Myeloid Leukemia Study: Retrospective Sectional Analysis of CML Patients
title_sort turkish chronic myeloid leukemia study: retrospective sectional analysis of cml patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874976/
https://www.ncbi.nlm.nih.gov/pubmed/24385824
http://dx.doi.org/10.4274/tjh.2013.0151
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