Electrotransfer of single-stranded or double-stranded DNA induces complete regression of palpable B16.F10 mouse melanomas

Enhanced tumor delivery of plasmid DNA with electric pulses in vivo has been confirmed in many preclinical models. Intratumor electrotransfer of plasmids encoding therapeutic molecules has reached Phase II clinical trials. In multiple preclinical studies, a reduction in tumor growth, increased survi...

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Detalles Bibliográficos
Autores principales: Heller, Loree, Todorovic, Vesna, Cemazar, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875131/
https://www.ncbi.nlm.nih.gov/pubmed/24287723
http://dx.doi.org/10.1038/cgt.2013.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875131/
https://www.ncbi.nlm.nih.gov/pubmed/24287723
http://dx.doi.org/10.1038/cgt.2013.71

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