Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells

Genome sequencing of single cells has a variety of applications, including characterizing difficult-to-culture microorganisms and identifying somatic mutations in single cells from mammalian tissues. A major hurdle in this process is the bias in amplifying the genetic material from a single cell, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gole, Jeff, Gore, Athurva, Richards, Andrew, Chiu, Yu-Jui, Fung, Ho-Lim, Bushman, Diane, Chiang, Hsin-I, Chun, Jerold, Lo, Yu-Hwa, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875318/
https://www.ncbi.nlm.nih.gov/pubmed/24213699
http://dx.doi.org/10.1038/nbt.2720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875318/
https://www.ncbi.nlm.nih.gov/pubmed/24213699
http://dx.doi.org/10.1038/nbt.2720

Ejemplares similares