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Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells
Genome sequencing of single cells has a variety of applications, including characterizing difficult-to-culture microorganisms and identifying somatic mutations in single cells from mammalian tissues. A major hurdle in this process is the bias in amplifying the genetic material from a single cell, a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875318/ https://www.ncbi.nlm.nih.gov/pubmed/24213699 http://dx.doi.org/10.1038/nbt.2720 |