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Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students

BACKGROUND: Previous evidence has shown that schizotypal personality disorder (SPD) is part of the schizophrenia spectrum. Few studies have examined latent classes in the developmental trajectories of SPD features over time in individuals with SPD features. METHODS: We adopted a longitudinal prospec...

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Autores principales: Geng, Fu-lei, Xu, Ting, Wang, Yi, Shi, Hai-song, Yan, Chao, Neumann, David L, Shum, David HK, Lui, Simon SY, Cheung, Eric FC, Chan, Raymond CK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875349/
https://www.ncbi.nlm.nih.gov/pubmed/24289659
http://dx.doi.org/10.1186/1471-244X-13-323
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author Geng, Fu-lei
Xu, Ting
Wang, Yi
Shi, Hai-song
Yan, Chao
Neumann, David L
Shum, David HK
Lui, Simon SY
Cheung, Eric FC
Chan, Raymond CK
author_facet Geng, Fu-lei
Xu, Ting
Wang, Yi
Shi, Hai-song
Yan, Chao
Neumann, David L
Shum, David HK
Lui, Simon SY
Cheung, Eric FC
Chan, Raymond CK
author_sort Geng, Fu-lei
collection PubMed
description BACKGROUND: Previous evidence has shown that schizotypal personality disorder (SPD) is part of the schizophrenia spectrum. Few studies have examined latent classes in the developmental trajectories of SPD features over time in individuals with SPD features. METHODS: We adopted a longitudinal prospective study design to follow up a cohort of 660 college students during a two-year period. Participants’ SPD-like symptoms and psychosocial function were measured by a comprehensive set of questionnaires that covered SPD features and cognitive, emotional, and psychosocial functions. Latent class growth analysis was used to examine the trajectory classes. RESULTS: Three trajectory classes were identified: a low, a medium, and a high SPD features group. Participants in the low group reported few SPD features and their symptoms declined over time. The medium group students had more SPD features than the low group and these symptoms stabilized during the follow up period. Participants in the high group reported the most SPD features and their symptoms increased over time. The three groups differed in paranoid thoughts, psychological distress, neurocognition function, and emotional expression over time. Results of multivariate regression analysis suggested that paranoid thoughts, emotional experience and prospective memory were predictors of social functioning in the high SPD feature group. CONCLUSIONS: Our findings suggest that individuals with SPD features may be delineated into different developmental subgroups and these subgroups differ significantly in psychosocial function. Delusions, emotion, and prospective memory may be important features to consider in early diagnosis and interventions for individuals predisposed to SPD and schizophrenia.
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spelling pubmed-38753492013-12-31 Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students Geng, Fu-lei Xu, Ting Wang, Yi Shi, Hai-song Yan, Chao Neumann, David L Shum, David HK Lui, Simon SY Cheung, Eric FC Chan, Raymond CK BMC Psychiatry Research Article BACKGROUND: Previous evidence has shown that schizotypal personality disorder (SPD) is part of the schizophrenia spectrum. Few studies have examined latent classes in the developmental trajectories of SPD features over time in individuals with SPD features. METHODS: We adopted a longitudinal prospective study design to follow up a cohort of 660 college students during a two-year period. Participants’ SPD-like symptoms and psychosocial function were measured by a comprehensive set of questionnaires that covered SPD features and cognitive, emotional, and psychosocial functions. Latent class growth analysis was used to examine the trajectory classes. RESULTS: Three trajectory classes were identified: a low, a medium, and a high SPD features group. Participants in the low group reported few SPD features and their symptoms declined over time. The medium group students had more SPD features than the low group and these symptoms stabilized during the follow up period. Participants in the high group reported the most SPD features and their symptoms increased over time. The three groups differed in paranoid thoughts, psychological distress, neurocognition function, and emotional expression over time. Results of multivariate regression analysis suggested that paranoid thoughts, emotional experience and prospective memory were predictors of social functioning in the high SPD feature group. CONCLUSIONS: Our findings suggest that individuals with SPD features may be delineated into different developmental subgroups and these subgroups differ significantly in psychosocial function. Delusions, emotion, and prospective memory may be important features to consider in early diagnosis and interventions for individuals predisposed to SPD and schizophrenia. BioMed Central 2013-11-29 /pmc/articles/PMC3875349/ /pubmed/24289659 http://dx.doi.org/10.1186/1471-244X-13-323 Text en Copyright © 2013 Geng et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Geng, Fu-lei
Xu, Ting
Wang, Yi
Shi, Hai-song
Yan, Chao
Neumann, David L
Shum, David HK
Lui, Simon SY
Cheung, Eric FC
Chan, Raymond CK
Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
title Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
title_full Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
title_fullStr Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
title_full_unstemmed Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
title_short Developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
title_sort developmental trajectories of schizotypal personality disorder-like behavioural manifestations: a two-year longitudinal prospective study of college students
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875349/
https://www.ncbi.nlm.nih.gov/pubmed/24289659
http://dx.doi.org/10.1186/1471-244X-13-323
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