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Omalizumab may decrease IgE synthesis by targeting membrane IgE+ human B cells

BACKGROUND: Omalizumab, is a humanized anti-IgE monoclonal antibody used to treat allergic asthma. Decreased serum IgE levels, lower eosinophil and B cell counts have been noted as a result of treatment. In vitro studies and animal models support the hypothesis that omalizumab inhibits IgE synthesis...

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Detalles Bibliográficos
Autores principales:	Chan, Marcia A, Gigliotti, Nicole M, Dotson, Abby L, Rosenwasser, Lanny J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875359/ https://www.ncbi.nlm.nih.gov/pubmed/24004581 http://dx.doi.org/10.1186/2045-7022-3-29

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