The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth

The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the ex...

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Autores principales: Lozano-Durán, Rosa, Macho, Alberto P, Boutrot, Freddy, Segonzac, Cécile, Somssich, Imre E, Zipfel, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Plant Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875382/
https://www.ncbi.nlm.nih.gov/pubmed/24381244
http://dx.doi.org/10.7554/eLife.00983
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author Lozano-Durán, Rosa
Macho, Alberto P
Boutrot, Freddy
Segonzac, Cécile
Somssich, Imre E
Zipfel, Cyril
author_facet Lozano-Durán, Rosa
Macho, Alberto P
Boutrot, Freddy
Segonzac, Cécile
Somssich, Imre E
Zipfel, Cyril
author_sort Lozano-Durán, Rosa
collection PubMed
description The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues. DOI: http://dx.doi.org/10.7554/eLife.00983.001
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spelling pubmed-38753822014-01-01 The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth Lozano-Durán, Rosa Macho, Alberto P Boutrot, Freddy Segonzac, Cécile Somssich, Imre E Zipfel, Cyril eLife Plant Biology The molecular mechanisms underlying the trade-off between plant innate immunity and steroid-mediated growth are controversial. Here, we report that activation of the transcription factor BZR1 is required and sufficient for suppression of immune signaling by brassinosteroids (BR). BZR1 induces the expression of several WRKY transcription factors that negatively control early immune responses. In addition, BZR1 associates with WRKY40 to mediate the antagonism between BR and immune signaling. We reveal that BZR1-mediated inhibition of immunity is particularly relevant when plant fast growth is required, such as during etiolation. Thus, BZR1 acts as an important regulator mediating the trade-off between growth and immunity upon integration of environmental cues. DOI: http://dx.doi.org/10.7554/eLife.00983.001 eLife Sciences Publications, Ltd 2013-12-31 /pmc/articles/PMC3875382/ /pubmed/24381244 http://dx.doi.org/10.7554/eLife.00983 Text en Copyright © 2013, Lozano-Durán et al http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Plant Biology
Lozano-Durán, Rosa
Macho, Alberto P
Boutrot, Freddy
Segonzac, Cécile
Somssich, Imre E
Zipfel, Cyril
The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth
title The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth
title_full The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth
title_fullStr The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth
title_full_unstemmed The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth
title_short The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth
title_sort transcriptional regulator bzr1 mediates trade-off between plant innate immunity and growth
topic Plant Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875382/
https://www.ncbi.nlm.nih.gov/pubmed/24381244
http://dx.doi.org/10.7554/eLife.00983
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