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MicroRNA Drop in the Bloodstream and MicroRNA Boost in the Tumour Caused by Treatment with Ribonuclease A Leads to an Attenuation of Tumour Malignancy
Novel data showing an important role of microRNAs in mediating tumour progression opened a new field of possible molecular targets for cytotoxic ribonucleases. Recently, antitumour and antimetastatic activities of pancreatic ribonuclease A were demonstrated and here genome-wide profiles of microRNAs...
Autores principales: | Mironova, Nadezhda, Patutina, Olga, Brenner, Evgenyi, Kurilshikov, Alexander, Vlassov, Valentin, Zenkova, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875445/ https://www.ncbi.nlm.nih.gov/pubmed/24386211 http://dx.doi.org/10.1371/journal.pone.0083482 |
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