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Low-Anxiety Rat Phenotypes Can Be Further Reduced through Genetic Intervention

BACKGROUND: A previous study using an intercross between the inbred rat strains Lewis (LEW) and Spontaneously Hypertensive Rats (SHR) identified a locus on chromosome 4, named Anxrr16, influencing an experimental index of anxiety and showing a transgressive effect, with alleles from the LEW strain (...

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Detalles Bibliográficos
Autores principales: de Medeiros, Gabriela Ferreira, Pereira, Elayne, Granzotto, Natalli, Ramos, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875470/
https://www.ncbi.nlm.nih.gov/pubmed/24386249
http://dx.doi.org/10.1371/journal.pone.0083666