Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4(+) T Cell Epitopes of Tumor-Associated Antigens

Reports have shown that activation of tumor-specific CD4(+) helper T (Th) cells is crucial for effective anti-tumor immunity and identification of Th-cell epitopes is critical for peptide vaccine-based cancer immunotherapy. Although computer algorithms are available to predict peptides with high bin...

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Detalles Bibliográficos
Autores principales: Yatsuda, Junji, Irie, Atsushi, Harada, Kumiko, Michibata, Yayoi, Tsukamoto, Hirotake, Senju, Satoru, Tomita, Yusuke, Yuno, Akira, Hirayama, Masatoshi, Abu Sayem, Mohammad, Takeda, Naoki, Shibuya, Isao, Sogo, Shinji, Fujiki, Fumihiro, Sugiyama, Haruo, Eto, Masatoshi, Nishimura, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875545/
https://www.ncbi.nlm.nih.gov/pubmed/24386437
http://dx.doi.org/10.1371/journal.pone.0084908

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