Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is notorious for its high invasiveness and metastatic ability. In this study, we identified a differential hypermethylated transcription repressor, Homeobox A2 (HOXA2), which may render NPC cells invasive and metastatic. Aberrant hypermethylation of HOXA2 led to low RN...

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Detalles Bibliográficos
Autores principales: Li, Hsin-Pai, Peng, Chen-Ching, Chung, I-Che, Huang, Mei-Yuan, Huang, Shao-Tung, Chen, Chia-Chun, Chang, Kai-Ping, Hsu, Cheng-Lung, Chang, Yu-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875777/
https://www.ncbi.nlm.nih.gov/pubmed/24243817

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