Cargando…
Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis
BACKGROUND: [(18) F]fluorodopa (FDOPA) positron emission tomography (PET) allows assessment of levodopa (LDOPA) metabolism and is widely used to study Parkinson's disease. We examined how [(18) F]FDOPA PET-derived kinetic parameters relate the dopamine (DA) and DA metabolite content of extracel...
Autores principales: | Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, Lee, Anna, Farrer, Matthew J, Stoessl, A Jon, Sossi, Vesna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875899/ https://www.ncbi.nlm.nih.gov/pubmed/24088510 http://dx.doi.org/10.1186/2191-219X-3-69 |
Ejemplares similares
-
Treadmill Running Combined with Microdialysis to Evaluate Motor Deficits and Improvement Following Dopaminergic Grafts in 6-OHDA Lesioned Rats
por: Hattori, S., et al.
Publicado: (1992) -
Use of [(18)F]FDOPA-PET for in vivo evaluation of dopaminergic dysfunction in unilaterally 6-OHDA-lesioned rats
por: Kyono, Kiyoshi, et al.
Publicado: (2011) -
Joint pattern analysis applied to PET DAT and VMAT2 imaging reveals new insights into Parkinson's disease induced presynaptic alterations
por: Fu, Jessie Fanglu, et al.
Publicado: (2019) -
Effects of Treadmill Exercise on the Recovery of Dopaminergic Neuron Loss and Muscle Atrophy in the 6-OHDA Lesioned Parkinson's Disease Rat Model
por: Choe, Myoung-Ae, et al.
Publicado: (2012) -
Novel data-driven, equation-free method captures spatio-temporal patterns of neurodegeneration in Parkinson's disease: Application of dynamic mode decomposition to PET
por: Fu, Jessie Fanglu, et al.
Publicado: (2019)