1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) Signaling Capacity and the Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer (NSCLC): Implications for Use of 1,25(OH)(2)D(3) in NSCLC Treatment

1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) exerts anti-proliferative activity by binding to the vitamin D receptor (VDR) and regulating gene expression. We previously reported that non-small cell lung cancer (NSCLC) cells which harbor epidermal growth factor receptor (EGFR) mutations display eleva...

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Detalles Bibliográficos
Autores principales: Upadhyay, Santosh Kumar, Verone, Alissa, Shoemaker, Suzanne, Qin, Maochun, Liu, Song, Campbell, Moray, Hershberger, Pamela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875951/
https://www.ncbi.nlm.nih.gov/pubmed/24217116
http://dx.doi.org/10.3390/cancers5041504

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