Optic neuritis due to immunobiologics: first Brazilian case report

The change in immunological response obtained by immunobiologics has brought a new paradigm to the treatment of immune-mediated disorders. As a result of their efficacy, there is a positive impact on the quality of life of patients. However, severe side effects, such as demyelination of cerebral or...

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Detalles Bibliográficos
Autores principales: da Silva, Luiz Gustavo Martins, Sasso, Letícia Soares, Nelli, Carlos José, Bernardes Filho, Fred, de Abreu, Marilda Aparecida Milanez Morgado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876011/
https://www.ncbi.nlm.nih.gov/pubmed/24346908
http://dx.doi.org/10.1590/abd1806-4841.20132295
Descripción
Sumario:The change in immunological response obtained by immunobiologics has brought a new paradigm to the treatment of immune-mediated disorders. As a result of their efficacy, there is a positive impact on the quality of life of patients. However, severe side effects, such as demyelination of cerebral or peripheral nerves, have been reported. After review of literature using PubMed and MEDLINE data from 2000 to 2012, we identified the cases correlating the biological uniterms and optic neuritis. This article reports the first Brazilian optic neuritis case associated with the use of immunobiologics. This publication is justified by the rarity of the disease and atypical therapeutical evolution.

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