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Cbl-b Enhances Sensitivity to 5-Fluorouracil via EGFR- and Mitochondria-Mediated Pathways in Gastric Cancer Cells

5-Fluorouracil (5-FU) is an essential component of anticancer chemotherapy against gastric cancer. However, the response rate of single drug is still limited. The ubiquitin ligase Cbl-b is a negative regulator of growth factor receptor signaling and is involved in the suppression of cancer cell prol...

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Detalles Bibliográficos
Autores principales:	Feng, Dan, Ma, Yanju, Liu, Jing, Xu, Ling, Zhang, Ye, Qu, Jinglei, Liu, Yunpeng, Qu, Xiujuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876118/ https://www.ncbi.nlm.nih.gov/pubmed/24351824 http://dx.doi.org/10.3390/ijms141224399

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