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Necrostatin-1 Attenuates Ischemia Injury Induced Cell Death in Rat Tubular Cell Line NRK-52E through Decreased Drp1 Expression

Necrostatin-1 (Nec-1) inhibits necroptosis and is usually regarded as having no effect on other cell deaths. Here, this study explored whether the addition of Nec-1 has an effect on cell death induced by simulated ischemia injury in rat tubular cell line NRK-52E. In addition, we also investigated th...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Jiang, Fen, Chen, Yuanhan, Luo, Jialun, Liu, Shuangxin, Zhang, Bin, Ye, Zhiming, Wang, Wenjian, Liang, Xinling, Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876139/
https://www.ncbi.nlm.nih.gov/pubmed/24351845
http://dx.doi.org/10.3390/ijms141224742