JAK-STAT signaling and myocardial glucose metabolism

JAK-STAT signaling occurs in virtually every tissue of the body, and so does glucose metabolism. In this review, we summarize the regulation of glucose metabolism in the myocardium and ponder whether JAK-STAT signaling participates in this regulation. Despite a paucity of data directly pertaining to...

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Detalles Bibliográficos
Autores principales: Frias, Miguel A, Montessuit, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876426/
https://www.ncbi.nlm.nih.gov/pubmed/24416656
http://dx.doi.org/10.4161/jkst.26458
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author Frias, Miguel A
Montessuit, Christophe
author_facet Frias, Miguel A
Montessuit, Christophe
author_sort Frias, Miguel A
collection PubMed
description JAK-STAT signaling occurs in virtually every tissue of the body, and so does glucose metabolism. In this review, we summarize the regulation of glucose metabolism in the myocardium and ponder whether JAK-STAT signaling participates in this regulation. Despite a paucity of data directly pertaining to cardiac myocytes, we conclude that JAK-STAT signaling may contribute to the development of insulin resistance in the myocardium in response to various hormones and cytokines.
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spelling pubmed-38764262014-01-10 JAK-STAT signaling and myocardial glucose metabolism Frias, Miguel A Montessuit, Christophe JAKSTAT Review JAK-STAT signaling occurs in virtually every tissue of the body, and so does glucose metabolism. In this review, we summarize the regulation of glucose metabolism in the myocardium and ponder whether JAK-STAT signaling participates in this regulation. Despite a paucity of data directly pertaining to cardiac myocytes, we conclude that JAK-STAT signaling may contribute to the development of insulin resistance in the myocardium in response to various hormones and cytokines. Landes Bioscience 2013-10-01 2013-09-27 /pmc/articles/PMC3876426/ /pubmed/24416656 http://dx.doi.org/10.4161/jkst.26458 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Review
Frias, Miguel A
Montessuit, Christophe
JAK-STAT signaling and myocardial glucose metabolism
title JAK-STAT signaling and myocardial glucose metabolism
title_full JAK-STAT signaling and myocardial glucose metabolism
title_fullStr JAK-STAT signaling and myocardial glucose metabolism
title_full_unstemmed JAK-STAT signaling and myocardial glucose metabolism
title_short JAK-STAT signaling and myocardial glucose metabolism
title_sort jak-stat signaling and myocardial glucose metabolism
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876426/
https://www.ncbi.nlm.nih.gov/pubmed/24416656
http://dx.doi.org/10.4161/jkst.26458
work_keys_str_mv AT friasmiguela jakstatsignalingandmyocardialglucosemetabolism
AT montessuitchristophe jakstatsignalingandmyocardialglucosemetabolism

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