SOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokines

SOCS3 is an inducible negative feedback inhibitor of cytokine signaling. Conditional deletion of SOCS3 in mice using the Cre-lox system has now been applied to a range of cell types in the steady-state and under inflammatory, pathogenic, or tumorigenic stress, with the resulting phenotypes demonstra...

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Detalles Bibliográficos
Autores principales: White, Christine A, Nicola, Nicos A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876435/
https://www.ncbi.nlm.nih.gov/pubmed/24416642
http://dx.doi.org/10.4161/jkst.25045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876435/
https://www.ncbi.nlm.nih.gov/pubmed/24416642
http://dx.doi.org/10.4161/jkst.25045

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