Cargando…

Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists

Histamine H3 receptor subtype has been the target of several recent drug development programs. Quantitative structure-activity relationship (QSAR) methods are used to predict the pharmaceutically relevant properties of drug candidates whenever it is applicable. The aim of this study was to compare t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dastmalchi, Siavoush, Hamzeh-Mivehroud, Maryam, Asadpour-Zeynali, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876572/ https://www.ncbi.nlm.nih.gov/pubmed/25317190

Ejemplares similares

An Alignment-Independent 3D-QSAR Study of FGFR2 Tyrosine Kinase Inhibitors
por: Jafari, Behzad, et al.
Publicado: (2017)

A Simple and Rapid Protocol for Producing Yeast Extract from Saccharomyces cerevisiae Suitable for Preparing Bacterial Culture Media
por: Zarei, Omid, et al.
Publicado: (2016)

6D-QSAR for predicting biological activity of human aldose reductase inhibitors using quasar receptor surface modeling
por: Sokouti, Babak, et al.
Publicado: (2023)

Highly efficient novel recombinant L-asparaginase with no glutaminase activity from a new halo-thermotolerant Bacillus strain
por: Safary, Azam, et al.
Publicado: (2019)

Alignment independent 3D-QSAR studies and molecular dynamics simulations for the identification of potent and selective S1P(1) receptor agonists
por: Alizadeh, Ali Akbar, et al.
Publicado: (2020)

In silico Evaluation of Crosslinking Effects on Denaturant m (eq) values and ΔCp upon Protein Unfolding
por: Hamzeh-Mivehroud, Maryam, et al.
Publicado: (2012)

Characterizing the Hot Spots Involved in RON-MSPβ Complex Formation Using In Silico Alanine Scanning Mutagenesis and Molecular Dynamics Simulation
por: Zarei, Omid, et al.
Publicado: (2017)

Expression and Biological Evaluation of an Engineered Recombinant L-asparaginase Designed by In Silico Method Based on Sequence of the Enzyme from Escherichia coli
por: Dastmalchi, Mahrokh, et al.
Publicado: (2023)

Identification of Novel Mutations in Arabidopsis thaliana DOF 4.2 Coding Gene
por: Jamshidi Kandjani, Omid, et al.
Publicado: (2021)

A QSAR Study on the 4-Substituted Coumarins as Potent Tubulin Polymerization Inhibitors
por: Dinparast, Leila, et al.
Publicado: (2020)

In-silico Investigation of Tubulin Binding Modes of a Series of Novel Antiproliferative Spiroisoxazoline Compounds Using Docking Studies
por: Abolhasani, Hoda, et al.
Publicado: (2015)

The Universal 3D QSAR Model for Dopamine D(2) Receptor Antagonists
por: Zięba, Agata, et al.
Publicado: (2019)

QSAR Modeling of Histamine H(3)R Antagonists/inverse Agonists as Future Drugs for Neurodegenerative Diseases
por: Corrêa, Michelle Fidelis, et al.
Publicado: (2018)

Characterization of Novel Fragment Antibodies Against TNF-alpha Isolated Using Phage Display Technique
por: Alizadeha, Ali Akbar, et al.
Publicado: (2019)

Effects of administration of histamine and its H(1), H(2), and H(3) receptor antagonists into the primary somatosensory cortex on inflammatory pain in rats
por: Tamaddonfard, Esmaeal, et al.
Publicado: (2014)

Multiple Targeting Approaches on Histamine H(3) Receptor Antagonists
por: Khanfar, Mohammad A., et al.
Publicado: (2016)

Anticonvulsant effects of isomeric nonimidazole histamine H(3) receptor antagonists
por: Sadek, Bassem, et al.
Publicado: (2016)

The Histamine H(4) Receptor Participates in the Neuropathic Pain-Relieving Activity of the Histamine H(3) Receptor Antagonist GSK189254
por: Borgonetti, Vittoria, et al.
Publicado: (2022)

2D-QSAR and 3D-QSAR Analyses for EGFR Inhibitors
por: Zhao, Manman, et al.
Publicado: (2017)

Pharmacophore Modelling and 3D-QSAR Studies on N(3)-Phenylpyrazinones as Corticotropin-Releasing Factor 1 Receptor Antagonists
por: Kaur, Paramjit, et al.
Publicado: (2012)

Rethinking 3D-QSAR
por: Cramer, Richard D.
Publicado: (2010)

Studies of New Fused Benzazepine as Selective Dopamine D3 Receptor Antagonists Using 3D-QSAR, Molecular Docking and Molecular Dynamics
por: Liu, Jing, et al.
Publicado: (2011)

Antiseizure Properties of Histamine H(3) Receptor Antagonists Belonging 3,4-Dihydroquinolin-2(1H)-Ones
por: Hua, Yi, et al.
Publicado: (2023)

Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism
por: Eissa, Nermin, et al.
Publicado: (2022)

The Multi-Targeting Ligand ST-2223 with Histamine H(3) Receptor and Dopamine D(2)/D(3) Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice
por: Eissa, Nermin, et al.
Publicado: (2021)

Effects of Olopatadine Hydrochloride, a Histamine H(1) Receptor Antagonist, on Histamine-Induced Skin Responses
por: Hashimoto, Takashi, et al.
Publicado: (2010)

The Three Dimensional Quantitative Structure Activity Relationships (3D-QSAR) and Docking Studies of Curcumin Derivatives as Androgen Receptor Antagonists
por: Xu, Guanhong, et al.
Publicado: (2012)

Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells
por: Baker, Jillian G
Publicado: (2008)

Ciproxifan, a histamine H(3) receptor antagonist, reversibly inhibits monoamine oxidase A and B
por: Hagenow, S., et al.
Publicado: (2017)

H(3) histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice
por: Dudek, Magdalena, et al.
Publicado: (2016)

The histamine H3 receptor antagonist thioperamide rescues circadian rhythm and memory function in experimental parkinsonism
por: Masini, D, et al.
Publicado: (2017)

Trisubstituted 1,3,5-Triazines as Histamine H(4) Receptor Antagonists with Promising Activity In Vivo
por: Olejarz-Maciej, Agnieszka, et al.
Publicado: (2023)

Expression, purification and DNA-binding properties of zinc finger domains of DOF proteins from Arabidopsis thaliana
por: Moghaddas Sani, Hakimeh, et al.
Publicado: (2018)

Covalent Inhibition of the Histamine H(3) Receptor
por: Wágner, Gábor, et al.
Publicado: (2019)

3D-QSAR reloaded: Open3DALIGN meets COSMOsar3D
por: Tosco, Paolo, et al.
Publicado: (2013)

The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors
por: Xu, Jian, et al.
Publicado: (2023)

Human Estrogen Receptor Alpha Antagonists, Part 3: 3-D Pharmacophore and 3-D QSAR Guided Brefeldin A Hit-to-Lead Optimization toward New Breast Cancer Suppressants
por: Kurtanović, Nezrina, et al.
Publicado: (2022)

The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats
por: Eissa, Nermin, et al.
Publicado: (2018)

The Neuroprotective Effects of Histamine H3 Receptor Antagonist E177 on Pilocarpine-Induced Status Epilepticus in Rats
por: Alachkar, Alaa, et al.
Publicado: (2019)

Histamine H3 Receptor Antagonist Enhances Neurogenesis and Improves Chronic Cerebral Hypoperfusion-Induced Cognitive Impairments
por: Wang, Na, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g2u729u2oc4cji822k0btbjgbh