Prenatal and Postnatal Polycyclic Aromatic Hydrocarbon Exposure, Airway Hyperreactivity, and Beta-2 Adrenergic Receptor Function in Sensitized Mouse Offspring

Despite data associating exposure to traffic-related polycyclic aromatic hydrocarbons (PAH) in asthma, mechanistic support has been limited. We hypothesized that both prenatal and early postnatal exposure to PAH would increase airway hyperreactivity (AHR) and that the resulting AHR may be insensitiv...

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Detalles Bibliográficos
Autores principales: Chu, Sophie, Zhang, Hanjie, Maher, Christina, McDonald, Jacob D., Zhang, Xiang, Ho, Shuk-Mei, Yan, Beizhan, Chillrud, Steven, Perera, Frederica, Factor, Phillip, Miller, Rachel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876588/
https://www.ncbi.nlm.nih.gov/pubmed/24454363
http://dx.doi.org/10.1155/2013/603581

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