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Cyclin B1 Destruction Box-Mediated Protein Instability: The Enhanced Sensitivity of Fluorescent-Protein-Based Reporter Gene System
The periodic expression and destruction of several cyclins are the most important steps for the exact regulation of cell cycle. Cyclins are degraded by the ubiquitin-proteasome system during cell cycle. Besides, a short sequence near the N-terminal of cyclin B called the destruction box (D-box; CDB)...
Autores principales: | Yang, Chao-Hsun, Kuo, Wan-Ting, Chuang, Yun-Ting, Chen, Cheng-Yu, Lin, Chih-Chien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876668/ https://www.ncbi.nlm.nih.gov/pubmed/24416725 http://dx.doi.org/10.1155/2013/732307 |
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