Silica-ZnCl(2): An Efficient Catalyst for the Synthesis of 4-Methylcoumarins

Silica-ZnCl(2) has been found to be an efficient and eco-friendly catalyst for the synthesis of substituted 4-methylcoumarins from ethyl acetoacetate and substituted phenols under “neat” conditions in an oil bath at 80°C. The experimental procedure is simple, includes shorter reaction times (15–65 m...

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Detalles Bibliográficos
Autores principales: Datta, Bandita, Pasha, Mohamed Afzal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876838/
https://www.ncbi.nlm.nih.gov/pubmed/24455295
http://dx.doi.org/10.1155/2013/132794
Descripción
Sumario:Silica-ZnCl(2) has been found to be an efficient and eco-friendly catalyst for the synthesis of substituted 4-methylcoumarins from ethyl acetoacetate and substituted phenols under “neat” conditions in an oil bath at 80°C. The experimental procedure is simple, includes shorter reaction times (15–65 min), compatible with sensitive functional groups, and results in excellent yield of the products.

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