Alcohol-Induced Liver Injury Is Modulated by Nlrp3 and Nlrc4 Inflammasomes in Mice

Alcoholic liver disease (ALD) is characterized by increased hepatic lipid accumulation (steatosis) and inflammation with increased expression of proinflammatory cytokines. Two of these cytokines, interleukin-1β (IL-1β) and IL-18, require activation of caspase-1 via members of the NOD-like receptor (...

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Detalles Bibliográficos
Autores principales: DeSantis, David A., Ko, Chih-wei, Liu, Yang, Liu, Xiuli, Hise, Amy G., Nunez, Gabriel, Croniger, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876912/
https://www.ncbi.nlm.nih.gov/pubmed/24453428
http://dx.doi.org/10.1155/2013/751374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876912/
https://www.ncbi.nlm.nih.gov/pubmed/24453428
http://dx.doi.org/10.1155/2013/751374

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