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Transcriptome Analysis in Prenatal IGF1-Deficient Mice Identifies Molecular Pathways and Target Genes Involved in Distal Lung Differentiation

BACKGROUND: Insulin-like Growth Factor 1 (IGF1) is a multifunctional regulator of somatic growth and development throughout evolution. IGF1 signaling through IGF type 1 receptor (IGF1R) controls cell proliferation, survival and differentiation in multiple cell types. IGF1 deficiency in mice disrupts...

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Detalles Bibliográficos
Autores principales:	Pais, Rosete Sofía, Moreno-Barriuso, Nuria, Hernández-Porras, Isabel, López, Icíar Paula, De Las Rivas, Javier, Pichel, José García
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877002/ https://www.ncbi.nlm.nih.gov/pubmed/24391734 http://dx.doi.org/10.1371/journal.pone.0083028

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