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Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection

BACKGROUND: High expression of CD161 on CD8+ T cells is associated with a population of cells thought to play a role in mucosal immunity. We wished to investigate this subset in an HIV and Mycobacterium tuberculosis (MTB) endemic African setting. METHODS: A flow cytometric approach was used to asses...

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Detalles Bibliográficos
Autores principales: Wong, Emily B., Akilimali, Ngomu Akeem, Govender, Pamla, Sullivan, Zuri A., Cosgrove, Cormac, Pillay, Mona, Lewinsohn, David M., Bishai, William R., Walker, Bruce D., Ndung'u, Thumbi, Klenerman, Paul, Kasprowicz, Victoria O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877057/
https://www.ncbi.nlm.nih.gov/pubmed/24391773
http://dx.doi.org/10.1371/journal.pone.0083474

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