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Loss of Multi-Epitope Specificity in Memory CD4(+) T Cell Responses to B. Pertussis with Age

Pertussis is still occurring in highly vaccinated populations, affecting individuals of all ages. Long-lived Th1 CD4(+) T cells are essential for protective immunity against pertussis. For better understanding of the limited immunological memory to Bordetella pertussis, we used a panel of Pertactin...

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Detalles Bibliográficos
Autores principales:	Han, Wanda G. H., van Twillert, Inonge, Poelen, Martien C. M., Helm, Kina, van de Kassteele, Jan, Verheij, Theo J. M., Versteegh, Florens G. A., Boog, Claire J. P., van Els, Cécile A. C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877060/ https://www.ncbi.nlm.nih.gov/pubmed/24391789 http://dx.doi.org/10.1371/journal.pone.0083583

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